The Road from Varangians to Greeks (Путь «из варяг в греки» in Russian) was the name of a water trade route in Kievan Rus', which connected Northern and Southern Rus', Baltic region and Scandinavia with the Byzantine Empire. The route began from the Varangian (Baltic) Sea along the Neva River and into the Lake Ladoga, then along the Volkhov River into the Lake Ilmen and over to the Lovat River . From there, the ships had to be portaged to the Dnieper River.

The Road from Varangians to Greeks was first mentioned in the Primary Chronicle. It appeared in the late 9th - early 10th century. The route gained significant importance in the 10th - first third of the 11th century. According to Constantine VII, the Krivichs and other tribes dependent on Kiev first transported hollowed-out lad'yas, or sailboats (called однодерёвки, which could accommodate 30 to 40 people) to Smolensk, Lubech , Chernigov and other cities. Then, these sailboats were transported along the Dnieper to Kiev. There, they were re-equipped, loaded with merchandise and sent downstream again. After passing the seven rapids (the merchants would portage their ships around the biggest of these rapids called Nenasytetsky) and a narrow, rocky spot called Krariyskaya crossing (where the merchants were often attacked by the Pechenegs), the businessmen stopped at the Khortitsa Island . Then, they equipped their ships with sails in the Dnieper estuary and continued to navigate along the western shore of the Black Sea all the way to Czargrad. The Road from Varangians to Greeks had different offshoots, such as along the Western Dvina between the Lovat and Dnieper and them for the Smolensk region along the Kasplya River . Another offshoot was along the Dnieper and the Usyazh-Buk River towards Lukoml and Polotsk.

The Road from Varangians to Greeks was connected to other waterways of Rus', such as the Pripyat-Bug waterway leading to Western Europe, and the Volga waterway leading to the Caspian Sea. The Road from Varangians to Greeks was used to transport different kinds of merchandise. Wine, spices, jewelry, glass, expensive fabrics, icons, and books came from the Byzantine Empire. Kiev used to trade bread, handmade goods, silver coins etc. Volhyn traded spinning wheels and other items. Certain kinds of weapon and handicrafts used to come from Scandinavia. Northern Rus' offered timber, fur, honey, wax. The Baltic tribes traded amber.

In the second half of the 11th century, Rus' strengthened its commercial ties with Western Europe, and the Road from Varangians to Greeks gradually lost its significance and made way for the Pripyat-Bug, Western Dvina and other waterways.