The Rhine-Main-Danube Canal (also called Main-Danube Canal, RMD Canal or Europa Canal) connects the Main and Danube from Bamberg by Nuremberg to Regensburg. It forms a constantly navigable connection from the Rhine delta in Rotterdam to the Danube Delta in the Black Sea. It was completed in 1992.

From Bamberg to Fürth the canal follows the valley of the Regnitz, a tributary of the Main. From Fürth to beyond Roth it follows the valley of the Rednitz , a tributary of the Regnitz. It crosses the Frankish Alb mountains and joins the river Altmühl near Beilngries . From Beilngries to Kelheim on the Danube the canal follows the Altmühl valley.