Oswine or Osuine (d. August 20, 651) was a King of Deira in northern England. He succeeded King Oswald of Northumbria, probably around the year 644, after Oswald's death at the Battle of Maserfield. Oswine was the son of Osric.

Oswine was highly praised by Bede for his saintly virtues. According to Bede, Oswine was murdered by Oswiu at Gilling after refusing to engage in battle.