Mithridates IV of Parthia ruled the western Parthian Empire from c. 129 to 140. He was the brother of Osroes I. During the invasion of Mesopotamia by the Roman emperor Trajan in 116 he took up the diadem but was defeated. After the death of Osroes in about 129 he assumed the throne and continued the struggle with the rival king Vologases II. He died in an attack on Commagene in about 140. He appointed his son Sanatruces successor, but Sanatruces fell in a battle with the Romans. Another son, Vologases IV, took the throne after the death of Vologases III died in 147.
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