Many makes and models of microcomputers could run, or ran from the outset, some version of the CP/M operating system. The following is an alphabetical list of some of those computers:
- ABC-24
- MITS Altair 8800
- Altos 580
- Amstrad CPC 464 (w/ DDI-1 disk drive interface)
- Amstrad CPC 6128 (and 664)
- Amstrad PCW 8256/8512/9512
- Amust Executive 816
- Apple II (with Microsoft Z80 Softcard)
- Aster CT-80
- Atari ST
- BBC Micro (with external Z80 module)
- Beehive Topper II
- Bigboard
- BMC IF800
- Bondwell 12, 14, 16
- Casio FP1000 FL
- Commodore 64 (with an infamously poor Z80 plug-in cartridge)
- Commodore 128 (with a Z80 on board along with its 8502)
- Compis
- Compupro
- Cromemco
- Datamax UV-1R
- DEC Rainbow 100/100+
- DEC VT-180 (aka Personal Computing Option, aka 'Robin')
- Epson PX-4, PX-8 (Geneva), QX-10, QX-16
- Exidy Sorcerer
- Heath/Zenith H90 and H89
- Hewlett-Packard HP-100
- Hobbit
- IBM PC
- IMSAI 8080
- Intel MDS-80
- Intertec Superbrain QD
- Iotec
- Kaypro
- LOBO Max-80
- LNW-80
- MCP (128K, Z80, S-100 bus)
- Applied Technology MicroBee (56KB+ RAM models)
- Megatel Quark
- MSX (some MSX-standard machines ran the CP/M-like MSX-DOS )
- Mycron 3
- NCR Decision mate V
- NEC APC
- NEC PC-8800
- Nelma Persona
- Northstar Horizon
- Nokia Mikromikko 1
- Osborne 1
- Osborne Vixen
- Otrona Attache
- Philips P2000T
- Processor Technology Sol-20 (optional)
- Research Machines 380Z and Link 480Z
- Sanyo MBC-1150
- Scandis
- Software Publisher's ATR8000
- ZX Spectrum +3
- Tandy TRS-80 model 4
- Televideo TS-802H
- Vector06c (Intel 8080, 16 color graphics, made in USSR)
- Xerox 820
- Yodobashi Formula-1
- Zenith Electronics Corporation Z-100
- Zorba
