Ernst Boepple (November 30, 1887 - December 14, 1949) was a Nazi politician.

Boepple originally served as the Bavarian Minister for Culture, but was replaced. On September 1, 1941, he was appointed the State Secretary of the General Government in Poland, serving as deputy to Deputy Governor Josef Buehler. Boepple was deeply implicated in the "Final Solution" as the deputy to Buehler and also held rank in the SS, being an Oberführer (Senior Colonel).

Boepple was sentenced to death by a Polish court and hanged on December 14, 1949.