Darien is the name of several places in the United States of America:

• Darien, Connecticut
• Darien, Georgia
• Darien, Illinois - a suburb of Chicago
• Darien, New York
• Darien, Wisconsin
• Darien (town), Wisconsin

Darién can also refer to places in Panama:

• Darién Province
• The town of Darién, founded by Vasco Núñez de Balboa.
• A short-lived colony of Scotland, see Darién scheme.

Darien was also the former transliteration of the name of Dalian, in China.