Claire Bretécher (born April 17, 1940) is a French cartoonist, known particularly for her portrayals of women and gender issues. Her creations include the Frustrés, and the unimpressed teenager Agrippina (reader of 'Heidegger in the Congo', a particularly un-PC joke on the Tintin series).

She was born in Nantes, and got her first break as an illustrator when she was asked to provide the artwork for The Rhesus Factor by René Goscinny. She went on to work for several popular magazines, and in 1969 invented the character "Cellulite". Throughout the 1970s and 1980s, she published successful collections, such as The Destiny of Monique (1982). One of her series of cartoons was adapted for television.