Chamberlain is a village in south-central Saskatchewan, Canada. Health Department statistics for 2003 put its population at 116.

Chamberlain is notable for being the last town between Regina and Saskatoon that Highway 11, the Louis Riel Trail , still passes through. The highway narrows to two lanes, and a number of small restaurants and gas stations benefit from having traffic pass through. The highway has been re-routed around other towns.