AMC is an abbreviation with the following meanings:

• Ayub Medical College - Pakistan
• Air Mobility Command - an American military organization
• All My Children, a popular American soap opera
• American Mathematics Competitions
• American Mathematics Contest - the first of the American Mathematics Competitions
• American Motors Corporation - an American automobile manufacturer
• American Movie Classics, a cable television all-movie channel
• American Muslim Council
• American Multi-Cinema Theatres
• Appalachian Mountain Club, ourdoors organization in the American northeast
• Armed Merchant Cruiser
• Army Material Command ([1])
• Asset management company
• Associated Motor Cycles Ltd a UK manufacturer of motorcycles
• Australian Mathematics Competition
• Automobile Manufacturing Company of London, makers of the AMC